Synapse 2
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Road Reimagined

Roll smooth, roll fast, roll confident. Wherever the road takes you, roll with Synapse – Cannondale's most comfortable, all-around, up-for-anything, pure road machine.

Model Description

Versatile performance meets refined comfort. The Synapse 2’s lightweight alloy frame keeps the ride rapid, responsive, and smooth, while Shimano’s new CUES U6000 road group offers durable, reliable shifting and braking. With proven DT Swiss 470 wheels and plenty of gear mounts, this is your go-anywhere, ride-forever companion.

What it's for

Enjoyable road riding with comfort, speed, and finesse

Highlights

  • Lightweight SmartForm C2 Alloy frame w/ full carbon fork
  • Durable, reliable, wide-range, 2x10-speed shifting from Shimano’s new CUES U6000 road group
  • Powerful, controllable braking from Shimano’s CUES hydraulic disc brakes
  • Proven all-around road performance from DT Swiss R 470 DB rims with Vittoria 700x30c tires

Cannondale

Synapse 2

$1,999.00

Size Guide

Jump to: MOUNTAIN | GRAVEL | ROAD | ELECTRIC | FITNESS

Mountain Bikes

Trail

4'6" - 5'2"
137 - 157 
 5'1" - 5'4"
154 - 162 
 5'3" - 5'8"
160 - 172 
  5'7" - 6'0" 
170 - 182 		  5'11" - 6'3" 
180 - 190 
XS S M L XL

Trail Women's

4'6" - 5'2"
137 - 157 
 5'1" - 5'4"
154 - 162 
 5'4" - 5'8"
162 - 172 
  5'7" - 6'0" 
170 - 182 
XS S M L

Trail SE

5'1" - 5'4"
154 - 162 
 5'4" - 5'8"
162 - 172 
  5'7" - 6'0" 
170 - 182 		  6'0" - 6'3" 
182 - 190 
S M L XL

Habit, Habit HT

5'0" - 5'2"
142 - 157 
 5'1" - 5'5"
154 - 165 
 5'4" - 5'9"
162 - 175 
  5'8" - 6'0" 
172 - 182 		  5'11" - 6'5" 
180 - 195 
XS S M L XL

Scalpel, Scalpel SE, Scalpel HT

5'1" - 5'5"
154 - 165 
 5'4" - 5'9"
162 - 175 
  5'8" - 6'0" 
172 - 182 		  5'11" - 6'5" 
180 - 195 
S M L XL

Jekyll

5'2" - 5'5"
157 - 165 
 5'4" - 5'9"
162 - 175 
  5'8" - 6'0" 
172 - 182 		  5'11" - 6'5" 
180 - 195 
S M L XL

Moterra, Moterra LT, Moterra SL

5'1" - 5'5"
154 - 165 
 5'4" - 5'9"
162 - 175 
  5'8" - 6'1" 
172 - 185 		  6'0" - 6'5" 
182 - 195 
S M L XL

Gravel

Topstone, Topstone Carbon

4'10" - 5'5"
147 - 165		 5'3" - 5'9"
160 - 175		 5'7" - 6'1"
170 - 185		  5'10" - 6'4" 
177 - 193		  6'0" - 6'8"
182 - 203
XS 
 
 S M L XL

SuperSix EVO SE, SuperSix EVO CX

5'0" - 5'4"
152 - 162
 5'5" - 5'9"
165 - 175 
 5'7" - 5'11"
170 - 180 
  5'10" - 6'1" 
177 - 185		  6'0" - 6'4" 
182 - 193
46cm 
 
 51cm 54cm 56cm 58cm

Road

Synapse

5'0 - 5'4"
152 - 162 
 5'2" - 5'6"
157 - 167 		 5'5" - 5'9"
165 - 175 		 5'7" - 5'11"
170 - 180 		  5'10" - 6'1" 
175 - 185		  6'0" - 6'4" 
182 - 193 		 6'3" - 6'8" 
190 - 203
44cm 48cm
 		 51cm 54cm 56cm 58cm 61cm

SuperSix Evo

5'1 - 5'5"
154 - 165 
 5'3" - 5'7"
160 - 170 		 5'5" - 5'9"
165 - 175 		 5'7" - 5'11"
170 - 180 		  5'10" - 6'1" 
177 - 185		  6'0" - 6'4" 
182 - 193 		 6'3" - 6'7" 
190 - 200
44cm
48cm
 		 51cm 54cm 56cm 58cm 61cm

SystemSix

5'3 - 5'7"
160 - 170 
 5'5" - 5'9"
165 - 175 		 5'7" - 5'11"
170 - 180 		 5'10" - 6'2"
177 - 187 		  6'10" - 6'4" 
182 - 193		  6'2" - 6'6" 
187 - 198 		 6'5" - 6'9" 
195 - 205
47cm 51cm
 		 54cm 56cm 58cm 60cm 62cm

CAAD Optimo

5'2" - 5'5"
157 - 165 
 5'3" - 5'7"
160 - 170 		 5'5" - 5'9"
165 - 175 		 5'7" - 5'11"
170 - 180 		  5'10" - 6'1" 
177 - 185		  6'0" - 6'4" 
182 - 193 
44cm 48cm
 		 51cm 54cm 56cm 58cm

CAAD13

5'3" - 5'7"
160 - 170 		 5'5" - 5'9"
165 - 175 		 5'4" - 5'9"
170 - 180 		  5'10" - 6'1" 
177 - 185		  6'0" - 6'4" 
182 - 193 		 6'2" - 6'6" 
187 - 198 
48cm
 		 51cm 54cm 56cm 58cm
60cm

Fitness, Urban & Comfort

Adventure, Adventure EQ

4'11" - 5'6"
149 - 167		 5'5" - 5'10"
165 - 177 
  5'9" - 6'2" 
175 - 187 
S M L

Quick, Quick Women's, Quick Remixte

4'10 - 5'3"
147 - 160 
 5'2" - 5'7"
157 - 170 		 5'5" - 5'10"
165 - 177 		 5'9" - 6'2"
175 - 187 		  6'0" - 6'5" 
182 - 195		  6'4" - 6'9" 
193 - 205 
XS S
 		 M L XL XXL

Quick CX

5'2" - 5'7"
157 - 170 
 5'5" - 5'10"
165 - 177 
 5'9" - 6'2"
175 - 187 
  6'0" - 6'5" 
182 - 195		  6'4" - 6'9" 
193 - 205
S 
 
 M L XL XXL

Quick CX Women's

4'10" - 5'3"
147 - 160 
 5'2" - 5'7"
157 - 170 
  5'5" - 5'10" 
165 - 177 
XS S M

Bad Boy

5'2" - 5'7"
157 - 170 
 5'5" - 5'10"
165 - 177 
  5'9" - 6'2" 
175 - 187 		  6'0" - 6'5" 
182 - 195 
S M L XL

Treadwell, Treadwell EQ

4'11" - 5'6"
149 - 167 
 5'4" - 6'0"
162 - 182 
  5'10" - 6'5" 
177 - 195 
S M L

Treadwell Remixte, Treadwell EQ Remixte

4'11" - 5'6"
149 - 167 
  5'4" - 6'0" 
162 - 182 
S L

Electric

Adventure Neo, Adventure Neo EQ

4'11" - 5'7"
149 - 170 
  5'7" - 6'6" 
170 - 198 
S L

Adventure Neo Allroad, Adventure Neo Allroad Low StepThru

5'0" - 5'7"
152 - 170
 5'5" - 5'10"
165 - 177 
  5'9" - 6'5" 
175 - 195 
S M L

Compact Neo

4'5" - 6'1"
134 - 185 
OS

Tesoro Neo SL, Tesoro Neo SL Remixte

5'4" - 5'8"
162 - 172
 5'7" - 6'0"
170 - 182 
  6'0" - 6'3" 
182 - 190 
S M L

Treadwell Neo, Treadwell Neo Remixte

4'11" - 5'6"
149 - 167
 5'4" - 6'0"
162 - 182 
  5'10" - 6'5" 
177 - 195 
S M L
In stock
PRO SETUP Expert Assembly 95% Ready to ride out of the box.
CERTIFIED Master Mechanic Assembly Precision dialed before shipping.
SINCE 1992 Over 30 Years of Trust Decades of cycling expertise.

SKU: C12104U1044

Road Reimagined

Roll smooth, roll fast, roll confident. Wherever the road takes you, roll with Synapse – Cannondale's most comfortable, all-around, up-for-anything, pure road machine.

Model Description

Versatile performance meets refined comfort. The Synapse 2’s lightweight alloy frame keeps the ride rapid, responsive, and smooth, while Shimano’s new CUES U6000 road group offers durable, reliable shifting and braking. With proven DT Swiss 470 wheels and plenty of gear mounts, this is your go-anywhere, ride-forever companion.

What it's for

Enjoyable road riding with comfort, speed, and finesse

Highlights

  • Lightweight SmartForm C2 Alloy frame w/ full carbon fork
  • Durable, reliable, wide-range, 2x10-speed shifting from Shimano’s new CUES U6000 road group
  • Powerful, controllable braking from Shimano’s CUES hydraulic disc brakes
  • Proven all-around road performance from DT Swiss R 470 DB rims with Vittoria 700x30c tires
SPECIFICATIONS

Here is the reformatted list for this Synapse build, featuring the Shimano CUES drivetrain. I’ve kept the structure consistent with your previous models for a clean Shopify storefront.

Technical Specifications

Frameset

  • Frame: Synapse, lightweight SmartForm C2 Alloy, SmartSense compatible, BSA threaded BB, internal cable routing, flat mount, 142x12 thru-axle, removable fender bridge, hidden rack/fender mounts
  • Fork: Synapse Carbon, integrated crown race, 12x100mm thru-axle, internal routing, flat mount brake, fender mounts
  • Headset: Integrated, 1-1/8" - 1-1/4"

Drivetrain

  • Rear Derailleur: Shimano CUES U6020
  • Front Derailleur: Shimano CUES U6030
  • Shifters: Shimano CUES U6030, 10-speed
  • Chain: Shimano LG500, 10-speed
  • Crank: Shimano CUES 6040, 46/32
  • Rear Cogs: Shimano CUES LG300, 11-39, 10-speed
  • Bottom Bracket: Shimano RS500, threaded

Brakes

  • Brakes: Shimano CUES hydraulic disc, 160/160mm RT64 rotors
  • Brake Levers: Shimano CUES hydraulic disc

Wheels

  • Rims: DT Swiss R470 DB, 28h, tubeless compatible
  • Hubs: (F) Formula CL-712, 12x100mm centerlock / (R) Formula RXC-400, 12x142mm centerlock
  • Spokes: Stainless Steel, 14g
  • Tires: Vittoria Zaffiro Pro V, 700x30c, reflective strip
  • Wheel Size: 700c

Components

  • Handlebar: Cannondale 3, 6061 Alloy, Compact
  • Stem: Cannondale 3, 6061 Alloy, 31.8, 7°
  • Grips: Cannondale Bar Tape, 3.5mm
  • Saddle: Fizik Aliante Delta, S-alloy rails
  • Seatpost: Cannondale 3, 6061 Alloy, 27.2x350mm

Details & Extras

  • Extra: Trainer axle end caps
  • Note: This model features SmartSense compatibility, allowing for easy integration of Cannondale’s light and radar system.
GEOMETRY

See the Synapse 2 in Action